Global small molecule API market will reach $360.0 billion by 2032, growing by 7.0% annually over 2022-2032, driven by the increasing incidences of diseases, the development of high-potency small molecule APIs, patents expiry of the top-selling pharmaceuticals, the increasing technological developments in manufacturing sector, and a surging healthcare expenditure.
Highlighted with 119 tables and 84 figures, this 187-page report “Global Small Molecule API Market 2022-2032 by Source (Synthetic, Semi-synthetic, Natural), Product Type (Standard, HPAPI), Therapeutic Area, Application (Clinical, Commercial), Manufacturer Type (Pharma, CMO), and Region: Trend Forecast and Growth Opportunity” is based on comprehensive research of the entire global small molecule API market and all its sub-segments through extensively detailed classifications. Profound analysis and assessment are generated from premium primary and secondary information sources with inputs derived from industry professionals across the value chain. The report is based on studies on 2020-2022 and provides forecast from 2023 till 2032 with 2022 as the base year. (Please note: The report will be updated before delivery so that the latest historical year is the base year, and the forecast covers at least 5 years over the base year.)
In-depth qualitative analyses include identification and investigation of the following aspects:
• Market Structure
• Growth Drivers
• Restraints and Challenges
• Emerging Product Trends & Market Opportunities
• Porter’s Fiver Forces
The trend and outlook of global market is forecast in optimistic, balanced, and conservative view by taking into account of COVID-19 and Russia-Ukraine conflict. The balanced (most likely) projection is used to quantify global small molecule API market in every aspect of the classification from perspectives of Source, Product Type, Therapeutic Area, Application, Manufacturer Type, and Region.
Based on Source, the global market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.
• Synthetic API
o Branded Synthetic API
o Generic Synthetic API
• Semi-synthetic API
• Natural Origin
Based on Product Type, the global market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.
• Standard API
• High Potency API (HPAPI)
o Branded HPAPI
o Generic HPAPI
By Therapeutic Area, the global market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.
• Infectious Diseases
• Oncology
• Ophthalmology
• Cardiovascular Disorders
• Central Nervous System
• Respiratory Disorders
• Metabolic Diseases
• Other Therapeutic Areas
By Application, the global market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.
• Clinical Use
• Commercial Use
By Manufacturer Type, the global market is segmented into the following sub-markets with annual revenue ($ mn) for 2022-2032 included in each section.
• Pharmaceutical Companies
• CMOs
Geographically, the following regions together with the listed national/local markets are fully investigated:
• North America (U.S., Canada, and Mexico)
• Europe (Germany, UK, France, Spain, Italy, Russia, Rest of Europe; Rest of Europe is further segmented into Netherlands, Switzerland, Poland, Sweden, Belgium, Austria, Ireland, Norway, Denmark, and Finland)
• APAC (Japan, China, South Korea, Australia, India, and Rest of APAC; Rest of APAC is further segmented into Malaysia, Singapore, Indonesia, Thailand, New Zealand, Vietnam, Taiwan, and Philippines)
• South America (Brazil, Chile, Argentina, Rest of South America)
• MEA (UAE, Saudi Arabia, South Africa, and Rest of MEA)
For each region and country, detailed analysis and annual revenue ($ mn) are available for 2022-2032. The breakdown of all regional markets by country and the breakdown of each national market by Product Type, Therapeutic Area, and Manufacturer Type over the forecast years are also included.
The report also covers the current competitive scenario and the predicted trend; and profiles key vendors including market leaders and important emerging players.
Selected Key Players:
Aurobindo Pharma Ltd.
Cambrex Corporation
Catalent Inc.
Dr. Reddy's Laboratories
GlaxoSmithKline plc
Lonza Group
Merck & Co., Inc.
Mylan N.V.
Novartis AG
Pfizer Inc.
Sun Pharmaceutical Industries Ltd.
Teva Pharmaceutical Industries Ltd.
Wuxi AppTec Co., Ltd.
(Please note: The report will be updated before delivery so that the latest historical year is the base year, and the forecast covers at least 5 years over the base year.)
1 Introduction 10
1.1 Industry Definition and Research Scope 10
1.1.1 Industry Definition 10
1.1.2 Research Scope 11
1.2 Research Methodology 14
1.2.1 Overview of Market Research Methodology 14
1.2.2 Market Assumption 15
1.2.3 Secondary Data 15
1.2.4 Primary Data 15
1.2.5 Data Filtration and Model Design 16
1.2.6 Market Size/Share Estimation 17
1.2.7 Research Limitations 18
1.3 Executive Summary 19
2 Market Overview and Dynamics 22
2.1 Market Size and Forecast 22
2.1.1 Impact of COVID-19 on World Economy 23
2.1.2 Impact of COVID-19 on the Market 26
2.1.3 Impact of Russia-Ukraine Conflict: War Slows Economic Recovery 28
2.2 Major Growth Drivers 32
2.3 Market Restraints and Challenges 36
2.4 Emerging Opportunities and Market Trends 39
2.5 Porter’s Fiver Forces Analysis 43
3 Segmentation of Global Market by Source 47
3.1 Market Overview by Source 47
3.2 Synthetic API 49
3.2.1 Branded Synthetic API 50
3.2.2 Generic Synthetic API 51
3.3 Semi-synthetic API 52
3.4 Natural Origin 53
4 Segmentation of Global Market by Product Type 54
4.1 Market Overview by Product Type 54
4.2 Standard API 56
4.3 High Potency API (HPAPI) 57
4.3.1 Branded HPAPI 58
4.3.2 Generic HPAPI 59
5 Segmentation of Global Market by Therapeutic Area 60
5.1 Market Overview by Therapeutic Area 60
5.2 Infectious Diseases 62
5.3 Oncology 63
5.4 Ophthalmology 64
5.5 Cardiovascular Disorders 65
5.6 Central Nervous System 66
5.7 Respiratory Disorders 67
5.8 Metabolic Diseases 68
5.9 Other Therapeutic Areas 69
6 Segmentation of Global Market by Application 70
6.1 Market Overview by Application 70
6.2 Clinical Use 72
6.3 Commercial Use 73
7 Segmentation of Global Market by Manufacturer Type 74
7.1 Market Overview by Manufacturer Type 74
7.2 Pharmaceutical Companies 76
7.3 CMOs 78
8 Segmentation of Global Market by Region 80
8.1 Geographic Market Overview 2022-2032 80
8.2 North America Market 2022-2032 by Country 84
8.2.1 Overview of North America Market 84
8.2.2 U.S. 88
8.2.3 Canada 91
8.2.4 Mexico 93
8.3 European Market 2022-2032 by Country 95
8.3.1 Overview of European Market 95
8.3.2 Germany 99
8.3.3 U.K. 101
8.3.4 France 103
8.3.5 Spain 105
8.3.6 Italy 107
8.3.7 Russia 109
8.3.8 Rest of European Market 111
8.4 Asia-Pacific Market 2022-2032 by Country 113
8.4.1 Overview of Asia-Pacific Market 113
8.4.2 Japan 117
8.4.3 China 120
8.4.4 Australia 122
8.4.5 India 124
8.4.6 South Korea 126
8.4.7 Rest of APAC Region 128
8.5 South America Market 2022-2032 by Country 130
8.5.1 Argentina 133
8.5.2 Brazil 135
8.5.3 Chile 137
8.5.4 Rest of South America Market 139
8.6 MEA Market 2022-2032 by Country 140
8.6.1 UAE 143
8.6.2 Saudi Arabia 145
8.6.3 South Africa 147
8.6.4 Other National Markets 149
9 Competitive Landscape 150
9.1 Overview of Key Vendors 150
9.2 New Product Launch, Partnership, Investment, and M&A 153
9.3 Company Profiles 154
Aurobindo Pharma Ltd. 154
Cambrex Corporation 156
Catalent Inc. 157
Dr. Reddy's Laboratories 160
GlaxoSmithKline plc 163
Lonza Group 167
Merck & Co., Inc. 170
Mylan N.V. 172
Novartis AG 174
Pfizer Inc. 176
Sun Pharmaceutical Industries Ltd. 180
Teva Pharmaceutical Industries Ltd. 183
Wuxi AppTec Co., Ltd. 185
RELATED REPORTS 187
List of Tables:
Table 1. Snapshot of Global Small Molecule API Market in Balanced Perspective, 2022-2032 20
Table 2. World Economic Outlook, 2021-2031 24
Table 3. World Economic Outlook, 2021-2023 25
Table 4. Scenarios for Economic Impact of Ukraine Crisis 29
Table 5. World Health Spending by Region, $ bn, 2013-2020 34
Table 6. World Top 10 Pharmaceutical Companies Based on Projected R&D Spending in 2026, $ bn 35
Table 7. Main Product Trends and Market Opportunities in Global Small Molecule API Market 39
Table 8. Global Small Molecule API Market by Source, 2022-2032, $ mn 47
Table 9. Global Small Molecule API Market: Synthetic API by Drug Type, 2022-2032, $ mn 49
Table 10. Global Small Molecule API Market by Product Type, 2022-2032, $ mn 54
Table 11. Global Small Molecule API Market: HPAPI by Drug Type, 2022-2032, $ mn 57
Table 12. Global Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 60
Table 13. Global Small Molecule API Market by Application, 2022-2032, $ mn 70
Table 14. Global Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 74
Table 15. Global Small Molecule API Market by Region, 2022-2032, $ mn 81
Table 16. Leading National Small Molecule API Market, 2022 and 2032, $ mn 83
Table 17. North America Small Molecule API Market by Country, 2022-2032, $ mn 86
Table 18. U.S. Small Molecule API Market by Product Type, 2022-2032, $ mn 90
Table 19. U.S. Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 90
Table 20. U.S. Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 90
Table 21. Canada Small Molecule API Market by Product Type, 2022-2032, $ mn 92
Table 22. Canada Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 92
Table 23. Canada Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 92
Table 24. Mexico Small Molecule API Market by Product Type, 2022-2032, $ mn 94
Table 25. Mexico Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 94
Table 26. Mexico Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 94
Table 27. Europe Small Molecule API Market by Country, 2022-2032, $ mn 98
Table 28. Germany Small Molecule API Market by Product Type, 2022-2032, $ mn 100
Table 29. Germany Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 100
Table 30. Germany Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 100
Table 31. U.K. Small Molecule API Market by Product Type, 2022-2032, $ mn 102
Table 32. U.K. Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 102
Table 33. U.K. Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 102
Table 34. France Small Molecule API Market by Product Type, 2022-2032, $ mn 104
Table 35. France Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 104
Table 36. France Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 104
Table 37. Spain Small Molecule API Market by Product Type, 2022-2032, $ mn 106
Table 38. Spain Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 106
Table 39. Spain Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 106
Table 40. Italy Small Molecule API Market by Product Type, 2022-2032, $ mn 108
Table 41. Italy Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 108
Table 42. Italy Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 108
Table 43. Russia Small Molecule API Market by Product Type, 2022-2032, $ mn 110
Table 44. Russia Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 110
Table 45. Russia Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 110
Table 46. Small Molecule API Market in Rest of Europe by Country, 2022-2032, $ mn 112
Table 47. APAC Small Molecule API Market by Country, 2022-2032, $ mn 115
Table 48. Japan Small Molecule API Market by Product Type, 2022-2032, $ mn 119
Table 49. Japan Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 119
Table 50. Japan Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 119
Table 51. China Small Molecule API Market by Product Type, 2022-2032, $ mn 121
Table 52. China Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 121
Table 53. China Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 121
Table 54. Australia Small Molecule API Market by Product Type, 2022-2032, $ mn 123
Table 55. Australia Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 123
Table 56. Australia Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 123
Table 57. India Small Molecule API Market by Product Type, 2022-2032, $ mn 125
Table 58. India Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 125
Table 59. India Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 125
Table 60. South Korea Small Molecule API Market by Product Type, 2022-2032, $ mn 127
Table 61. South Korea Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 127
Table 62. South Korea Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 127
Table 63. Small Molecule API Market in Rest of APAC by Country/Region, 2022-2032, $ mn 129
Table 64. South America Small Molecule API Market by Country, 2022-2032, $ mn 132
Table 65. Argentina Small Molecule API Market by Product Type, 2022-2032, $ mn 134
Table 66. Argentina Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 134
Table 67. Argentina Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 134
Table 68. Brazil Small Molecule API Market by Product Type, 2022-2032, $ mn 136
Table 69. Brazil Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 136
Table 70. Brazil Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 136
Table 71. Chile Small Molecule API Market by Product Type, 2022-2032, $ mn 138
Table 72. Chile Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 138
Table 73. Chile Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 138
Table 74. MEA Small Molecule API Market by Country, 2022-2032, $ mn 142
Table 75. UAE Small Molecule API Market by Product Type, 2022-2032, $ mn 144
Table 76. UAE Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 144
Table 77. UAE Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 144
Table 78. Saudi Arabia Small Molecule API Market by Product Type, 2022-2032, $ mn 146
Table 79. Saudi Arabia Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 146
Table 80. Saudi Arabia Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 146
Table 81. South Africa Small Molecule API Market by Product Type, 2022-2032, $ mn 148
Table 82. South Africa Small Molecule API Market by Therapeutic Area, 2022-2032, $ mn 148
Table 83. South Africa Small Molecule API Market by Manufacturer Type, 2022-2032, $ mn 148
Table 84. Aurobindo Pharma Ltd.: Company Snapshot 154
Table 85. Aurobindo Pharma Ltd.: Business Segmentation 155
Table 86. Aurobindo Pharma Ltd.: Product Portfolio 155
Table 87. Cambrex Corporation: Company Snapshot 156
Table 88. Catalent Inc.: Company Snapshot 157
Table 89. Catalent Inc.: Business Segmentation in 2018 157
Table 90. Catalent Inc.: Product Portfolio 158
Table 91. Catalent Inc.: Revenue, 2018-2020, $ million 158
Table 92. Catalent Inc.: Revenue by Region in 2018 159
Table 93. Dr. Reddy's Laboratories: Company Snapshot 160
Table 94. Dr. Reddy's Laboratories: Business Segmentation 160
Table 95. Dr. Reddy's Laboratories: Revenue, 2018-2020, $ bn 161
Table 96. GlaxoSmithKline: Company Snapshot 163
Table 97. GlaxoSmithKline: Business Segmentation 164
Table 98. GlaxoSmithKline: Product Portfolio 165
Table 99. GlaxoSmithKline: Revenue, 2018-2020, $ bn 166
Table 100. Lonza Group: Company Snapshot 167
Table 101. Lonza Group: Business Segmentation in 2018 167
Table 102. Lonza Group: Product Portfolio 168
Table 103. Lonza Group: Revenue by Region in 2018 168
Table 104. Merck & Co., Inc.: Company Snapshot 170
Table 105. Merck & Co., Inc.: Business Segmentation 170
Table 106. Merck & Co., Inc.: Revenue, 2018-2020, $ bn 171
Table 107. Mylan NV: Company Snapshot 172
Table 108. Mylan NV: Revenue, 2017-2019, $ bn 173
Table 109. Novartis International AG: Company Snapshot 174
Table 110. Novartis International AG: Business Segmentation 174
Table 111. Novartis International AG: Revenue, 2017-2019, $ bn 175
Table 112. Pfizer Inc.: Company Snapshot 176
Table 113. Pfizer Inc.: Business Segmentation 177
Table 114. Pfizer Inc.: Product Portfolio 178
Table 115. Pfizer Inc.: Revenue, 2018-2020, $ bn 178
Table 116. Sun Pharmaceutical Industries Limited: Company Snapshot 180
Table 117. Teva Pharmaceutical Industries Ltd.: Company Snapshot 183
Table 118. Teva Pharmaceutical Industries Ltd.: Business Segmentation 184
Table 119. WuXi AppTec Inc.: Company Snapshot 185
